Scientists Grow Teeth From Gum Cells.
Main Category: Dentistry
Also Included In: Stem Cell Research
Article Date: 11 Mar 2013 - 3:00 PDT
Scientists took cells from adult human gum tissue.
The day a new "biotooth" can be grown in the gap left by a missing tooth as an alternative to having a false one implanted came a step closer recently when UK researchers revealed how they have developed a way to bioengineer new teeth from a person's own gum cells.
However, it may be some years before what has been achieved in the lab is available to patients sitting in the dentist's chair. The researchers had to combine the human gum cells with a type of embryonic mouse cell to instruct the gum cells to make teeth. The next challenge is to find a human adult cell that can be coaxed to do the same.
Paul Sharpe, a professor at King's College London, and colleagues, report their work in the 4 March online before print issue of theJournal of Dental Research.
Read full Article : http://www.medicalnewstoday.com/articles/257480.php
However, it may be some years before what has been achieved in the lab is available to patients sitting in the dentist's chair. The researchers had to combine the human gum cells with a type of embryonic mouse cell to instruct the gum cells to make teeth. The next challenge is to find a human adult cell that can be coaxed to do the same.
Paul Sharpe, a professor at King's College London, and colleagues, report their work in the 4 March online before print issue of theJournal of Dental Research.
Read full Article : http://www.medicalnewstoday.com/articles/257480.php
Cadaver stem cells offer new hope of life after death (News Scientist)- 02 January 2013 by Jessica Hamzelou.
A PERSON'S organs can be used after they die, and now their stem cells might be harvested too. Huge numbers of stem cells can be mined from bone marrow up to five days after death and used in a variety of life-saving treatments.
Human bone marrow contains mesenchymal stem cells (MSCs), which can develop into a variety of cell types, including bone, cartilage and fat. They can be transplanted from one person to another, with the type of cell they form depending on where in the body they are injected. Cells injected into the heart, for example, can become healthy cardiac tissue, a useful therapy for people with chronic heart conditions.
Unlike other tissue transplants, MSCs tend not to be rejected by the recipient's immune system. In fact, MSCs appear to pacify immune cells.
Read full article : http://www.newscientist.com/article/dn23034-cadaver-stem-cells-offer-new-hope-of-life-after-death.html
Human bone marrow contains mesenchymal stem cells (MSCs), which can develop into a variety of cell types, including bone, cartilage and fat. They can be transplanted from one person to another, with the type of cell they form depending on where in the body they are injected. Cells injected into the heart, for example, can become healthy cardiac tissue, a useful therapy for people with chronic heart conditions.
Unlike other tissue transplants, MSCs tend not to be rejected by the recipient's immune system. In fact, MSCs appear to pacify immune cells.
Read full article : http://www.newscientist.com/article/dn23034-cadaver-stem-cells-offer-new-hope-of-life-after-death.html
Stem Cells From Human Adipose Tissue Used To Chase Migrating Cancer Cells.
Tuesday, March 12, 2012 - Stem Cell Research News - Basic Research
In laboratory studies, researchers have found that stem cells from a patient’s own fat may have the potential to deliver new treatments directly into the brain after the surgical removal of a glioblastoma, the most common and aggressive form of brain tumor.
The Johns Hopkins investigators said so-called mesenchymal stem cells (MSCs) have an unexplained ability to seek out damaged cells, such as those involved in cancer, and may provide clinicians a new tool for accessing difficult-to-reach parts of the brain where cancer cells can hide and proliferate anew.The biggest challenge in brain cancer is the migration of cancer cells. Even when we remove the tumor, some of the cells have already slipped away and are causing damage somewhere else
The Johns Hopkins investigators said so-called mesenchymal stem cells (MSCs) have an unexplained ability to seek out damaged cells, such as those involved in cancer, and may provide clinicians a new tool for accessing difficult-to-reach parts of the brain where cancer cells can hide and proliferate anew.The biggest challenge in brain cancer is the migration of cancer cells. Even when we remove the tumor, some of the cells have already slipped away and are causing damage somewhere else
Read full article : http://www.stemcellresearchnews.com/absolutenm/anmviewer.asp?a=3102&z=9
Need an organ? Just print some stem cells in 3D
- 00:01 05 February 2013 by Douglas Heaven
- For similar stories, visit the Stem Cells Topic Guide
Printing blobs of human embryonic stem cells is the latest step towards being able to grow organs on demand.
Researchers had already used inkjet printers to print out 2D cultures of living cells. But printing blobs of cells rather than flat sheets is closer to real tissue.
Human embryonic stem cells are pluripotent, which means they are capable of becoming a cell in any type of tissue, making them attractive to those who are trying to grow new organs. But it is hard to print them, says Wenmiao Shu at Heriot-Watt University in Edinburgh, UK, because they are sensitive to manipulation. So Shu has modified a valve-based printer nozzle so it gently squirts out cells in blobs rather than a single layer.
The blobs have structural rigidity, says Shu, so could be used to grow organs without a scaffold. "They are like building blocks" says Shu.
"It's a nice piece of work," says Brian Derby at the University of Manchester, UK. "If you put a blob of cells down it will fuse into clumps, which is closer to how it is in the body." But he would like to see more evidence that the cells retain their pluripotency after being printed.
Read full Article : http://www.newscientist.com/article/dn23133-need-an-organ-just-print-some-stem-cells-in-3d.html